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GPR135 polyclonal antibody

GPR135 polyclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human
Applications	WB, IHC
Amount	100ul
Host	Rabbit
Item no.	BS62379-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	Forkhead box protein N4; FOXN4
Swiss-Prot	Q96NZ1
Application_all	WB: 1:500ca.1000
Background	Forkhead box protein N4, transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Purification And Purity	The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	FOXN4 polyclonal antibody detects endogenous levels of FOXN4 protein.
BiowMW	ca.55 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic peptide, corresponding to Human FOXN4.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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