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Anti-Calpain 1 Antibody Picoband™ (monoclonal, 2E3)

Anti-Calpain 1 Antibody Picoband™ (monoclonal, 2E3)

Item no.	BOS-M01943-4
Manufacturer	Boster
Amount	100 ug/vial
Category	Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Western Blot Proliferation Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized
Applications	WB, FC
Clone	2E3
Specific against	Human
Host	Mouse
Isotype	IgG2b
Citations	1. Smith IJ, et al. Calpain activity is increased in skeletal muscle from gastric cancer patients with no or minimal weight loss. Muscle Nerve, 2011 Mar.<br/>2. Wang JC, et al. Proteolysis by endogenous calpain I leads to the activation of calcineurin in human heart. Clin Lab, 2012.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CAPN1; CANPL1; PIG30; Calpain-1 catalytic subunit; EC 3.4.22.52; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; Calpain-1 large subunit; Cell proliferation-inducing gene 30 protein; Micromolar-calpain; muCANP
Available
Manufacturers Product Category	Primary Antibodies, Mouse Monoclonal Antibodies
Short Description	Boster Bio Anti-Calpain 1 Antibody Picoband™ (monoclonal, 2E3) catalog # M01943-4. Tested in Flow Cytometry, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-Calpain 1 Antibody Picoband™ (monoclonal, 2E3) catalog # M01943-4. Tested in Flow Cytometry, WB applications. This antibody reacts with Human.
Background	CAPN1 is also known as CANP or muCL. The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
Gene Name	CAPN1
Application Details	Western blot, 0.25-0.5μg/ml, Human Flow Cytometry, 1-3μg/1x10⁶ cells, Human
Application Notes	Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Monoclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.
Immunogen	E.coli-derived human Calpain 1 recombinant protein (Position: Q396-A555). Human Calpain 1 shares 86% amino acid (aa) sequence identity with both mouse and rat Calpain 1.
Purification	Immunogen affinity purified.
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Molecular Weight	82 kDa

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/vial

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Delivery expected until 9/13/2024

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