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Anti-SHC Antibody Picoband™ (monoclonal, 6D6E1)

Anti-SHC Antibody Picoband™ (monoclonal, 6D6E1)

Item no.	BOS-M00796-3
Manufacturer	Boster
Amount	100 ug/vial
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized
Applications	WB
Clone	6D6E1
Specific against	Human, Mouse, Rat
Host	Mouse
Isotype	IgG2b
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Manufacturers Product Category	Primary Antibodies, Mouse Monoclonal Antibodies
Short Description	Boster Bio Anti-SHC Antibody Picoband™ (monoclonal, 6D6E1) catalog # M00796-3. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-SHC Antibody Picoband™ (monoclonal, 6D6E1) catalog # M00796-3. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Background	SHC, also known as SHC1 (SHC-transforming protein 1) or SHCA, is a protein that in humans is encoded by the SHC1 gene. SCOP classifies the 3D structure as belonging to the SH2 domain family. This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.
Gene Name	SHC1
Application Details	Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Application Notes	Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Monoclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human SHC, identical to the related mouse and rat sequences.
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Molecular Weight	65 kDa

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/vial

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Delivery expected until 8/30/2024

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