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Anti-Synaptophysin/SYP Picoband™ Antibody

Anti-Synaptophysin/SYP Picoband™ Antibody

Item no.	BOS-A05049
Manufacturer	Boster
Amount	100 ug/vial
Category	Antibodies Primary Antibodies
Type	Antibody
Format	Lyophilized
Applications	WB, IF, IHC, ICC
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Synaptophysin; Major synaptic vesicle protein p38; SYP
Available
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Short Description	Boster Bio Anti-Synaptophysin/SYP Picoband™ Antibody catalog # A05049. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-Synaptophysin/SYP Picoband™ Antibody catalog # A05049. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
Background	Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene. It is mapped to Xp11.23. This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability.
Gene Name	SYP
Application Details	Western blot, 0.1-0.25μg/ml, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section, 2-5 μg/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5μg/ml, Human Immunofluorescence, 5μg/ml, Mouse, Rat
Application Notes	Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin/SYP, which shares 91.3% amino acid (aa) sequence identity with both mouse and rat Synaptophysin/SYP.
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins.
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	synaptophysin
Molecular Weight	38 kDa
Protein Function	Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Subcellular Localization	Synaptic vesicle membrane. Multi-pass membrane protein. Synaptosome.
Tissue Specificity	Ubiquitous in adult tissues. Detected in osteoblasts of the perichondrium in the developing limb of 12-week old embryos. Isoform 1 is detected in fetal brain, lung, kidney and testis. Isoform 2 is detected in fetal testis, and at much lower levels in fetal brain, lung and kidney.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/vial

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Delivery expected until 8/30/2024

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