« Back
Home /
Anti-Sprouty 4/Spry-4/SPRY4 Antibody Picoband™

Anti-Sprouty 4/Spry-4/SPRY4 Antibody Picoband™

Item no.	BOS-A04343-2
Manufacturer	Boster
Amount	100 ug/vial
Category	Antibodies Primary Antibodies
Type	Antibody
Format	Lyophilized
Applications	WB, FC, IHC, ELISA
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein sprouty homolog 4; Spry-4; SPRY4
Available
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Short Description	Boster Bio Anti-Sprouty 4/Spry-4/SPRY4 Antibody Picoband™ catalog # A04343-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-Sprouty 4/Spry-4/SPRY4 Antibody Picoband™ catalog # A04343-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.
Background	Protein sprouty homolog 4 is a protein that in humans is encoded by the SPRY4 gene. It is mapped to 5q31.3. This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants.
Gene Name	SPRY4
Application Details	Western blot, 0.25-0.5μg/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human Flow Cytometry, 1-3μg/1x10⁶ cells, Human Direct ELISA, 0.1-0.5μg/ml, Human
Application Notes	Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Immunogen	E.coli-derived human Sprouty 4/Spry-4/SPRY4 recombinant protein (Position: M1-K297).
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins.
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	sprouty RTK signaling antagonist 4
Molecular Weight	35 kDa
Protein Function	Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.
Subcellular Localization	Ruffle membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug/vial

available

Delivery expected until 9/13/2024

Express Delivery: Save 11 days

Compare

Add to wishlist

Recommend by mail