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NELF-A Antibody

NELF-A Antibody

Item no.	BM-CAF20369-100ug
Manufacturer	Biomatik
Amount	100ug
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Immunogen	A synthesized peptide derived from human NELF-A.
Conjugation	Unconjugated
Specificity	NELF-A Antibody detects endogenous levels of NELF-A.
Gene ID	7469
Gene Name	NELFA
Swiss-Prot	Q9H3P2
Purification	The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Storage	NELF-A
Expiry Date	1mg/ml
Shipping Condition	-20C
Comments	1 year
Technical Notes	Ice packs
Restriction	Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. In vitro, the NELFA:NELFCD subcomplex binds to ssDNA and ssRNA in a sequence- and structure-dependent manner. Probably required to interact with the RNA polymerase II complex.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 11/29/2024

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