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MSH3 Antibody

MSH3 Antibody

Manufacturer	Biomatik
Category	Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Rat
Isotype	IgG
Applications	WB, IF, IHC, ICC, ELISA
Amount	100ug
Host	Rabbit
Item no.	BM-CAF17519-100ug
eClass 6.1	32160702
eClass 9.0	32160702
Available
Immunogen	A synthesized peptide derived from human MSH3
Conjugation	Unconjugated
Specificity	MSH3 Antibody detects endogenous levels of total MSH3
Gene ID	4437
Gene Name	MSH3
Swiss-Prot	P20585
Purification	The antiserum was purified by peptide affinity chromatography.
Concentration	1mg/ml
Storage	-20C
Expiry Date	1 year
Shipping Condition	Ice packs
Comments	Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Technical Notes	WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC: 1:100-1:500
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Delivery expected until 8/30/2024

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