Item no. |
AP50790 |
Manufacturer |
Abcepta
|
Amount |
100 ul |
Category |
|
Type |
Antibody Primary |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
LPCAT2, LPAAT-alpha, AYTL1, LysoPAFAT, 1-acylglycerophosphocholine O-acyltransferase, 1-alkylglycerophosphocholine O-acetyltransferase, Acetyl-CoA:lyso-PAF acetyltransferase, Acetyl-CoA:lyso-platelet-activating factor acetyltransferase, Acyltransferase-like 1, LPC acyltransferase 2, LPCAT-2, Lyso-PAF acetyltransferase, LysoPC acyltransferase 2, Lysophosphatidylcholine acyltransferase 2, 1-acylglycerol-3-phosphate O-acyltransferase 11, 1-AGP acyltransferase 11, 1-AGPAT 11, Lysophosphatidic acid acyltransferase alpha, AGPAT11 |
Available |
|
Primary Accession |
Q7L5N7 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet- activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso- PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3- phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1, 2- diacyl-sn-glycero-3-phosphocholine. |
Bio References |
Shindou H., et al.J. Biol. Chem. 282:6532-6539(2007).Ota T., et al.Nat. Genet. 36:40-45(2004).Bechtel S., et al.BMC Genomics 8:399-399(2007).Agarwal A.K., et al.J. Lipid Res. 51:2143-2152(2010).Burkard T.R., et al.BMC Syst. Biol. 5:17-17(2011). |
Clonality |
Polyclonal |
Gene ID |
54947 |
Gene Name |
LPCAT2 |
Subtitle |
Affinity-Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of lysate from A549 cell line, using LPCAT2 Antibody(AP50790). AP50790 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
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