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Phospho-RB-S795 Rabbit mAb

Phospho-RB-S795 Rabbit mAb

Manufacturer	Abclonal
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human
Isotype	IgG
Applications	WB, ELISA, IHC-P
Amount	200 uL
Item no.	AP1384-200uL
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	42030590
Available
Alias	RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
Purity	Affinity purification
Background	The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Manufacturers Category	Phosphorylated Antibodies
Immunogen	A synthetic phosphorylated peptide around S795 of human RB.
Storage	Store at -20℃. Avoid freeze / thaw cycles.\|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilution	WB, 1:500 - 1:1000\|IHC-P, 1:100 - 1:500
Protein Size	106kDa
Manufacturers Research Area	Epigenetics Nuclear Signaling, Transcription Factors, DNA Damage Repair, Protein phosphorylation, Cancer, Tumor suppressors, Cell Biology Developmental Biology, Cell Cycle, Cell cycle inhibitors, Cell Cycle Control-G1 S Checkpoint
Gene Symbol	RB1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 uL

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Delivery expected until 7/26/2024

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