Item no. |
AP1075-50ul |
Manufacturer |
Abclonal
|
Amount |
50ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
Purity |
Affinity purification |
Sequence |
DTYVE |
NCBI |
CSF1R |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
CSF1R;C-FMS;CD115;CSF-1R;CSFR;FIM2;FMS;HDLS;M-CSF-R;BANDDOS |
Similar products |
CSF1R, FMS, FIM2, C-FMS, CD115, CSFR, HDLS, CSF-1R, M-CSF-R, BANDDOS |
Available |
|
Background |
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. |
Route |
Synthetic peptide |
Manufacturers Category |
Phosphorylated Antibodies |
Immunogen |
A synthetic phosphorylated peptide around Y723 of human CSF1R (NP_005202.2). |
Storage |
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Recommended Dilution |
WB, 1:500 - 1:1000 |
Protein Size |
108kDa |
Manufacturers Research Area |
Protein phosphorylation, Signal Transduction, Kinase, Tyrosine kinases, Immunology Inflammation, CDs, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway, Stem Cells, Cardiovascular, Angiogenesis |
Gene Symbol |
CSF1R |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.