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Prothymosin Alpha (PTMA)

Prothymosin Alpha (PTMA)

Manufacturer	Anogen
Category	Oncology Antibodies Western Blot ELISA Primary Antibodies By Organ Bladder Cancer Breast Cancer Heart & Blood Cancer Testicular & Prostate Cancer Gastric Cancer
Type	Antibody Monoclonal
Specific against	Human
Clone	4A7
Isotype	IgG1 kappa
Format	Aff. Pur
Applications	WB, ELISA
Amount	0.5mg
Host	Mouse
Item no.	ANOG-MO-T40087I
eClass 6.1	32160702
eClass 9.0	42030590
Available
Description	Mouse monoclonal antibody to human prothymosin alpha (PTMA)
Target Protein	Human prothymosin alpha (PTMA)
Immunogen	A short peptide (eeaengrdapangnan) derived from PTMA was conjugated with KLH for immunization.
Specificity	This antibody is reactive to PTMA peptide (eeaengrdapangnan) and GST tagged recombinant PTMA protein.
Purification	Protein G affinity purified
Species Reactivity	Human, others not tested
Myeloma	Sp2/0-Ag14
Background	PTMA (prothymosin alpha) is the precursor of thymosin alpha1. It is an acidic, non-histone nuclear protein with 109-111 amino acids. PTMA is implicated with cell cycle regulation, chromatin remodeling, expression of oxidative stress-response genes and immuno-modulation. PTMA is elevated in malignances such as breast cancer, gastric cancer, prostate and bladder cancers. PTMA is a potential biomarker for the prognosis of cancer treatment.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	Western blot: This antibody is reactive to GST tagged 38.4KD recombinant PTMA protein. ELISA: Biotin labelled anti-PTMA clone 4A7 can be used as detection antibody for PTMA detection in combination with anti-PTMA clone 1F2, 4G2, 6H7 or 6A3 as capture antibody. The detectable dose is approximately 0.5ng/mL.
Research Area	Chromatin-remodelling, cell proliferation, oncology
Storage	Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 8/16/2024

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