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mAb anti-Human EGF

mAb anti-Human EGF

Item no.	ANOG-MO-C40044F-0.1mg
Manufacturer	Anogen
Amount	0.1mg
Category	Antibodies Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Applications	WB, ICC, ELISA, IS
Clone	S-146
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Description	Mouse monoclonal antibody to human epidermal growth factor (EGF)
Target Protein	Human EGF
Immunogen	Purified recombinant human EGF, 6kDa, 53 amino acid residues
Specificity	Reactive with natural and recombinant human EGF.
Purification	Protein G affinity purified
Cross Reactivity	Does not cross react with other human cytokines tested such as IL-1beta, IL-8, MCAF, TGF-beta and SAA.
Myeloma	Sp2/0-Ag14
Light chain	Kappa
Background	Epidermal growth factor (EGF), along with its receptor EGFR, plays an important role in cell proliferation, differentiation and survival. The binding of EGF to EGFR triggers the intrinsic tyrosine kinase activity of EGFR, activates signalling molecules and stimulates the synthesis of proteins and DNAs. EGF is crucial for maintaining mucosal lining in gastrointestinal duct and for healing of oral and gastro esophageal ulcers. EGF signalling is needed for cancer growth. Monoclonal antibodies that block EGFR have been applied for lung cancer and colon inhibition.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution	Double distilled water is recommended to reconstitute the antibody
Research Area	Cytokines and Growth Factors
Storage	Store at -20oC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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Delivery expected until 2/21/2025

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