Comparison

mAb anti-Human MCP-1

Item no. ANOG-MO-C40021D-0.1mg
Manufacturer Anogen
Amount 0.1mg
Category
Type Antibody Monoclonal
Applications WB, ELISA, IS
Clone S101
Specific against Human
Host Mouse
Isotype IgG1 kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Available
Description
Mouse monoclonal antibody to human Monocyte Chemotactic Protein-1 (MCP-1)/ Monocyte Chemotactic and Activating Factor (MCAF)
Target Protein
Human MCP-1
Immunogen
Purified recombinant human MCP-1
Specificity
This antibody reacts with natural and recombinant human MCP-1.
Purification
Protein G affinity purified
Cross Reactivity
This antibody does not react with human interleukin-8 (IL-8) and other human cytokines tested such as interleukin-1beta (IL-1beta), serum amyloid A (SAA) and epidermal growth factor (EGF).
Myeloma
Sp2/0-Ag14
Light chain
Kappa
Background
Monocyte chemotactic and activating factor (MCAF) is also called monocyte chemotactic protein-1 (MCP-1) and chemokine (C-C motif) ligand 2 (CCL2). It is primarily secreted by monocytes, macrophages and dendritic cells. This cytokine displays chemotactic activity for monocytes, T-cells, and basophils, but not for neutrophils or eosinophils. MCAF causes the degranulation of basophils and mast cells, and augments the activity of monocyte and macrophage. MCAF plays an important role in inflammation, angiogenesis, auto-immune diseases, renal diseases, chronic infection and granuloma formation.
Formulation
Lyophilized from a solution in 0.01M PBS, pH 7.2
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Research Area
Cytokines and Growth Factors
Storage
Store at -20oC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1mg
Available: In stock
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