Comparison

Interleukin-8 (IL-8)

Item no. ANOG-AI60001
Manufacturer Anogen
Amount 1.0mg
Category
Type Antibody Polyclonal
Format Purified
Applications WB, ELISA, NT
Specific against Human (Homo sapiens)
Host Chicken
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products IL-8
Available
Description
Chicken anti-human Interleukin-8 polyclonal antibody (IgY fraction).
Target Protein
Human IL-8
Immunogen
Highly purified recombinant human IL-8
Specificity
This antibody recognizes human Interleukin-8 (IL-8)
Purification
Protein G affinity purified
Species Reactivity
Human, others not tested
Cross Reactivity
This polyclonal antibody exhibits no detectable cross-reactivity with human serum albumin, bovine serum albumin, and other cytokines tested such as IL-1beta, IL-16, TNF-alpha, GM-CSF, MCSF, bFGF and MIP-1alpha.
Background
Interleukin 8 (IL-8), like IL-6, is secreted by macrophages and a variety of cells that express Toll-like receptors in response to the stimulation of pathogens. IL-8's primary function is to recruit neutrophils and other target cells through chemotaxis to the infected site to eliminate pathogens. IL-8 causes increased intracellular Ca2+, release of reactive oxygen species, and other physiological changes required for migration and phagocytosis. IL-8 is also known to promote angiogenesis.
Formulation
Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00mg/mL
Application info
ELISA: The antibody when used at 2.6ng/mL can detect recombinant human IL-8 coated on ELISA plate.Neutralization: Total chicken IgY fraction at the concentration of 50 ug/mL showed 60% inhibition of 10ng/mL IL-8 induced IL8RB/293 cell migration
Western Blot: The antibody, when used at concentration of 0.26 ug/mL will allow visualization of recombinant human IL-8.
Research Area
Cytokine, interleukin and chemotaxis
Storage
Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1.0mg
Available: In stock
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