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Proto-Oncogene Vav (VAV1) Antibody

Proto-Oncogene Vav (VAV1) Antibody

Item no.	abx011903-100
Manufacturer	Abbexa
Amount	100 ul
Category	Antibodies Flow Cytometry Western Blot ELISA Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, FC, ELISA
Specific against	Human
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Manufacturers Category	Primary Antibodies
Description	The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.
Dry Ice	No
Buffer	PBS, containing 0.05% sodium azide.
Clonality	Monoclonal
Gene Symbol	VAV1
Molecular Weight	98.3 kDa
Note	This product is for research use only.
OMIM	164875
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Target Information	Proto-Oncogene Vav (VAV1)
UniProt Entry Name	VAV_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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