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ACAT1 Antibody (C-term)

ACAT1 Antibody (C-term)

Item no.	ABC-AW5517-U100
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ACAT1, mitochondrial, MAT, ACAT, T2, Acetyl-CoA acetyltransferase, Acetoacetyl-CoA thiolase
Available
Primary Accession	P24752
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in the gene encoding ACAT1 are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Bio References	Locke, J.A., Prostate 68 (1), 20-33 (2008) Guo, Z.Y., Biochemistry 46 (35), 10063-10071 (2007) Haapalainen, A.M., Biochemistry 46 (14), 4305-4321 (2007)
Clonality	Polyclonal
Gene ID	38
Gene Name	ACAT1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	All lanes : Anti-ACAT1 Antibody (C-term) at 1:1000 dilution Lane 1: HepG2 whole cell lysates Lane 2: mouse liver lysates Lane 3: SK-BR-3 whole cell lysates Lane 4: SW620 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 45 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ACAT1 antibody (C-term) (Cat.#AW5517), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Isotype	Rabbit Ig
Calculated MW	45200
Antigen Region	311-349
Antigen Source	HUMAN
Target/Specificity	This ACAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-349 amino acids from the C-terminal region of human ACAT1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/4/2024