Item no. |
ABC-AW5349-U100 |
Manufacturer |
Abcepta
|
Amount |
100 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
TYK2, Non-receptor tyrosine-protein kinase TYK2 |
Available |
|
Primary Accession |
P29597 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. |
Bio References |
Firmbach-Kraft I., et al.Oncogene 5:1329-1336(1990).Velazquez L., et al.Cell 70:313-322(1992).Krolewski J.J., et al.Oncogene 5:277-282(1990).Partanen J., et al.Proc. Natl. Acad. Sci. U.S.A. 87:8913-8917(1990).Colamonici O., et al.Mol. Cell. Biol. 14:8133-8142(1994). |
Clonality |
Polyclonal |
Gene ID |
7297 |
Gene Name |
TYK2 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of lysates from Hela cell line, mouse liver tissue lysate(from left to right), using TYK2 Antibody (C-term)(Cat. #AW5349). AW5349 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Immunohistochemical analysis of paraffin-embedded H. liver section using TYK2 Antibody (C-term)(Cat#AW5349). AW5349 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:25 |
Other Accession |
Q9R117 |
Isotype |
Rabbit Ig |
Calculated MW |
133650 |
Antigen Region |
887-922 |
Antigen Source |
HUMAN |
Target/Specificity |
This TYK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 887-922 amino acids from the C-terminal region of human TYK2. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.