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SOX2 Antibody (C-term)

SOX2 Antibody (C-term)

Item no.	ABC-AW5343-U100
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SOX2, Transcription factor SOX-2
Available
Primary Accession	P48431
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Bio References	Stevanovic M., et al.Mamm. Genome 5:640-642(1994). Sadler L.A., et al.Submitted (DEC-1992) to the EMBL/GenBank/DDBJ databases. Fantes J., et al.Nat. Genet. 33:461-463(2003). Takahashi K., et al.Cell 131:861-872(2007). Rigbolt K.T., et al.Sci. Signal. 4:RS3-RS3(2011).
Clonality	Polyclonal
Gene ID	6657
Gene Name	SOX2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of lysates from F9, NCCIT cell line (from left to right), using SOX2 Antibody (C-term)(Cat. #AW5343). AW5343 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	P48430; P54231
Predicted	C, Sh
Isotype	Rabbit Ig
Calculated MW	34310
Antigen Region	282-316
Antigen Source	HUMAN
Target/Specificity	This SOX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/4/2024

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