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PARP3 Antibody (N-term)

PARP3 Antibody (N-term)

Item no.	ABC-AW5272-U100
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PARP3;ADPRT3; ADPRTL3; Poly [ADP-ribose] polymerase 3; Poly [ADP-ribose] polymerase 3; ADP-ribosyltransferase diphtheria toxin-like 3; Poly [ADP-ribose] polymerase 3; IRT1; Poly [ADP-ribose] polymerase 3; NAD(+) ADP-ribosyltransferase 3; Poly [ADP-ribose]
Available
Primary Accession	Q9Y6F1
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Clonality	Polyclonal
Gene ID	10039
Gene Name	PARP3 {ECO:0000303\|PubMed:10329013, ECO:0000312\|HGNC:HGNC:273}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysates from K562, MDA-MB-453, NCI-H292, A549, Hela, CEM cell line (from left to right), using PARP3 Antibody (N-term)(Cat. #AW5272). AW5272 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
Type image 1	WB
Dilution image 1	1:1000
Isotype	Rabbit Ig
Calculated MW	60089
Antigen Region	99-126
Antigen Source	Human
Target/Specificity	This PARP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-126 amino acids from the N-terminal region of human PARP3.
NCBI Accession	NP_001003931.2; NP_005476.3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-AW5272-U100-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 9/6/2024