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HDAC1 Antibody(C-term)

HDAC1 Antibody(C-term)

Item no.	ABC-AW5103-U100
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	HDAC1; RPD3L1; Histone deacetylase 1
Available
Primary Accession	Q13547
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Bio References	Yang, Z., et al. Clin. Chem. Lab. Med. 48(12):1785-1791(2010) Grausenburger, R., et al. J. Immunol. 185(6):3489-3497(2010) Miller, K.M., et al. Nat. Struct. Mol. Biol. 17(9):1144-1151(2010) Brandt, S., et al. Int. J. Biochem. Cell Biol. 42(9):1472-1481(2010) Leone, V., et al. Oncogene 29(30):4341-4351(2010)
Clonality	Polyclonal
Gene ID	3065
Gene Name	HDAC1 (HGNC:4852)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, Rat
Legend image 1	Western blot analysis of lysates from Hela, K562 cell line, rat spleen tissue lysate (from left to right), using HDAC1 Antibody (C-term)(Cat. #AW5103). AW5103 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q4QQW4; O09106; Q32PJ8; NP_004955.2
Predicted	B, M
Isotype	Rabbit Ig
Calculated MW	55103
Antigen Region	421-450
Antigen Source	HUMAN
Target/Specificity	This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human HDAC1.
NCBI Accession	NP_004955.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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