Item no. |
ABC-AW5103-U100 |
Manufacturer |
Abcepta
|
Amount |
100 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
HDAC1; RPD3L1; Histone deacetylase 1 |
Available |
|
Primary Accession |
Q13547 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
Histone acetylation and deacetylation, catalyzed bymultisubunit complexes, play a key role in the regulation ofeukaryotic gene expression. The protein encoded by this genebelongs to the histone deacetylase/acuc/apha family and is acomponent of the histone deacetylase complex. It also interactswith retinoblastoma tumor-suppressor protein and this complex is akey element in the control of cell proliferation anddifferentiation. Together with metastasis-associated protein-2, itdeacetylates p53 and modulates its effect on cell growth andapoptosis. |
Bio References |
Yang, Z., et al. Clin. Chem. Lab. Med. 48(12):1785-1791(2010)Grausenburger, R., et al. J. Immunol. 185(6):3489-3497(2010)Miller, K.M., et al. Nat. Struct. Mol. Biol. 17(9):1144-1151(2010)Brandt, S., et al. Int. J. Biochem. Cell Biol. 42(9):1472-1481(2010)Leone, V., et al. Oncogene 29(30):4341-4351(2010) |
Clonality |
Polyclonal |
Gene ID |
3065 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, Rat |
Legend image 1 |
Western blot analysis of lysates from Hela, K562 cell line, rat spleen tissue lysate (from left to right), using HDAC1 Antibody (C-term)(Cat. #AW5103). AW5103 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
Q4QQW4; O09106; Q32PJ8; NP_004955.2 |
Predicted |
B, M |
Isotype |
Rabbit Ig |
Calculated MW |
55103 |
Antigen Region |
421-450 |
Antigen Source |
HUMAN |
Target/Specificity |
This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human HDAC1. |
NCBI Accession |
NP_004955.2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.