Item no. |
ABC-AW5070-U100 |
Manufacturer |
Abcepta
|
Amount |
100 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Applications |
WB, FC |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
USP11, UHX1, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11 |
Available |
|
Primary Accession |
P51784 |
Antigen Type |
Recombinant Protein |
Application |
WB, FC |
Bio Background |
Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. |
Bio References |
Ross M.T., et al.Nature 434:325-337(2005).Ideguchi H., et al.Biochem. J. 367:87-95(2002).Swanson D.A., et al.Hum. Mol. Genet. 5:533-538(1996).Schoenfeld A.R., et al.Mol. Cell. Biol. 24:7444-7455(2004).Yamaguchi T., et al.J. Biol. Chem. 282:33943-33948(2007). |
Clonality |
Monoclonal |
Gene ID |
8237 |
Gene Name |
USP11 |
Subtitle |
Purified Mouse Monoclonal Antibody (Mab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of lysates from Jurkat, Hela cell line (from left to right), using USP11 Antibody (C-term R565)(Cat. #AW5070). AW5070 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Flow cytometric analysis of Hela cells using USP11 Antibody (C-term R565)(green, Cat#AW5070) compared to an isotype control of mouse IgG1(blue). AW5070 was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody. |
Type image 2 |
FC |
Dilution image 2 |
1:25 |
Isotype |
IgG1, κ |
Calculated MW |
109817 |
Antigen Region |
32-300 |
Antigen Source |
HUMAN |
Target/Specificity |
This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.