Item no. |
ABC-AT4381a |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Applications |
WB, IF, ELISA |
Clone |
100000 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
TSPAN8, TM4SF3, Transmembrane 4 superfamily member 3, Tetraspanin-8, Tspan-8, Tumor-associated antigen CO-029 |
Available |
|
Primary Accession |
P19075 |
Antigen Type |
Recombinant Protein |
Application |
WB, IF, E |
Bio Background |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. |
Bio References |
1.TM4SF3 promotes esophageal carcinoma metastasis via upregulating ADAM12m expression.Zhou Z, Ran YL, Hu H, Pan J, Li ZF, Chen LZ, Sun LC, Peng L, Zhao XL, Yu L, Sun LX, Yang ZH.Clin Exp Metastasis. 2008; 25(5):537-48. Epub 2008 Mar 26. |
Clonality |
Monoclonal |
Gene ID |
7103 |
Gene Name |
TSPAN8 |
Subtitle |
Mouse monoclonal antibody raised against a partial recombinant TSPAN8. |
Reactivity |
H |
Legend image 1 |
Immunofluorescence of monoclonal antibody to TSPAN8 on 293 cell . [antibody concentration 10 ug/ml] |
Type image 1 |
IF |
Legend image 2 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.3 KDa) . |
Type image 2 |
WB |
Dilution image 2 |
1:500~1000 |
Legend image 3 |
Western Blot analysis of TSPAN8 expression in transfected 293T cell line by TSPAN8 monoclonal antibody (M02), clone 1E5.
Lane 1: TSPAN8 transfected lysate (Predicted MW: 26.1 KDa). Lane 2: Non-transfected lysate. |
Type image 3 |
WB |
Dilution image 3 |
1:500~1000 |
Legend image 4 |
Detection limit for recombinant GST tagged TSPAN8 is approximately 10ng/ml as a capture antibody. |
Type image 4 |
E |
Other Accession |
NM_004616 |
Isotype |
IgG3 Lambda |
Target/Specificity |
TSPAN8 (NP_004607, 110 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
NCBI Accession |
NP_004607.1 |
|
Clone: 100000 |
Org Accession |
NP_004607 |
Concentration |
0.4mg/ml |
Gene Description |
tetraspanin 8 |
Gene Summary |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq |
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