Comparison

STK6 Antibody (monoclonal) (M01)

Item no. ABC-AT4091a
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications WB, IF, IHC, ELISA
Clone 5F8
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products AURKA, Aurora kinase A, Aurora 2, Aurora/IPL1-related kinase 1, Serine/threonine-protein kinase 6, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, ARK-1, hARK1, Aurora-related kinase 1, Serine/threonine-protein kinase aurora-A
Available
Primary Accession
O14965
Antigen Type
Recombinant Protein
Application
WB, IHC, IF, E
Bio Background
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Bio References
1.KIBRA Protein Phosphorylation Is Regulated by Mitotic Kinase Aurora and Protein Phosphatase 1.Xiao L, Chen Y, Ji M, Volle DJ, Lewis RE, Tsai MY, Dong J.J Biol Chem. 2011 Oct 21; 286(42):36304-15. Epub 2011 Aug 30.2.Aurora Kinase A expression is associated with lung cancer histological-subtypes and with tumor de-differentiation.Lo Iacono M, Monica V, Saviozzi S, Ceppi P, Bracco E, Papotti M, Scagliotti GV.J Transl Med. 2011 Jun 30; 9:100.
Clonality
Monoclonal
Gene ID
6790
Gene Name
AURKA
Subtitle
Mouse monoclonal antibody raised against a partial recombinant STK6.
Reactivity
H
Legend image 1
Immunofluorescence of monoclonal antibody to STK6 on HeLa cell. [antibody concentration 30 ug/ml]
Type image 1
IF
Legend image 2
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
Type image 2
WB
Dilution image 2
1:500~1000
Legend image 3
STK6 monoclonal antibody (M01), clone 5F8 Western Blot analysis of STK6 expression in Hela S3 NE ( (Cat # AT4091a )
Type image 3
WB
Dilution image 3
1:500~1000
Legend image 4
Immunoperoxidase of monoclonal antibody to AURKA on formalin-fixed paraffin-embedded human prostate. [antibody concentration 6 ug/ml]
Type image 4
IHC
Legend image 5
Detection limit for recombinant GST tagged STK6 is approximately 0.1ng/ml as a capture antibody.
Type image 5
E
Other Accession
NM_198433
Isotype
IgG2a Kappa
Target/Specificity
AURKA (NP_940835, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession
NP_003591.2; NP_940835.1; NP_940836.1; NP_940837.1; NP_940838.1; NP_940839.1
Clone: 5F8
Org Accession
NP_940835
Concentration
0.5 mg/ml
Gene Description
aurora kinase A
Gene Summary
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close