Item no. |
ABC-AT4024a |
Manufacturer |
Abcepta
|
Amount |
200 ul |
Category |
|
Type |
Antibody Primary |
Format |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Applications |
WB |
Clone |
4G3 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
SPINLW1, Eppin, EPPIN, WAP7, WFDC7, Cancer/testis antigen 71, CT71, Epididymal protease inhibitor, Protease inhibitor WAP7, Serine protease inhibitor-like with Kunitz and WAP domains 1, WAP four-disulfide core domain protein 7 |
Available |
|
Primary Accession |
O95925 |
Antigen Type |
Recombinant Protein |
Application |
WB |
Bio Background |
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Bio References |
Variants of the EPPIN gene affect the risk of idiopathic male infertility in the Han-Chinese population. Ding X, et al. Hum Reprod, 2010 Jul. PMID 20488803.Variants in the Eppin gene show association with semen quality in Han-Chinese population. Ding X, et al. Reprod Biomed Online, 2010 Jan. PMID 20158997.Analysis of recombinant human semenogelin as an inhibitor of human sperm motility. Mitra A, et al. Biol Reprod, 2010 Mar. PMID 19889947.The effect of anti-eppin antibodies on ionophore A23187-induced calcium influx and acrosome reaction of human spermatozoa. Zhang J, et al. Hum Reprod, 2010 Jan. PMID 19801569.Molecular mechanism of epididymal protease inhibitor modulating the liquefaction of human semen. Wang ZJ, et al. Asian J Androl, 2008 Sep. PMID 18645681. |
Clonality |
Monoclonal |
Gene ID |
100526773; 57119 |
Gene Name |
EPPIN |
Subtitle |
Mouse monoclonal antibody raised against a partial recombinant SPINLW1. |
Reactivity |
H |
Legend image 1 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (38.06 KDa) . |
Type image 1 |
WB |
Dilution image 1 |
1:500~1000 |
Other Accession |
NM_020398 |
Isotype |
IgM Kappa |
Antigen Source |
Human: ~~ Positive |
Target/Specificity |
SPINLW1 (NP_065131, 22 a.a. ~ 133 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
NCBI Accession |
NP_001185915.1; NP_065131.1 |
|
Clone: 4G3 |
Org Accession |
NP_065131 |
Gene Description |
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin) |
Gene Summary |
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.