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KLRC3 Antibody (monoclonal) (M01)

KLRC3 Antibody (monoclonal) (M01)

Item no.	ABC-AT2644a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB, ELISA
Clone	3D5
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	KLRC3, NKG2E, NKG2-E type II integral membrane protein, NK cell receptor E, NKG2-E-activating NK receptor
Available
Primary Accession	Q07444
Antigen Type	Recombinant Protein
Application	WB, E
Bio Background	Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Bio References	1.Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells.Cheray M, Petit D, Forestier L, Karayan-Tapon L, Maftah A, Jauberteau MO, Battu S, Gallet FP, Lalloue F.Cancer Letters (2011), doi: 10.1016/ j.canlet.2011.07.027
Clonality	Monoclonal
Gene ID	3823
Gene Name	KLRC3
Subtitle	Mouse monoclonal antibody raised against a partial recombinant KLRC3.
Reactivity	H
Legend image 1	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .
Type image 1	WB
Dilution image 1	1:500~1000
Legend image 2	Detection limit for recombinant GST tagged KLRC3 is approximately 0.3ng/ml as a capture antibody.
Type image 2	E
Other Accession	NM_002261
Isotype	IgG2a Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	KLRC3 (NP_002252, 132 a.a. ~ 240 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_002252.2; NP_031359.2
	Clone: 3D5
Org Accession	NP_002252
Gene Description	killer cell lectin-like receptor subfamily C, member 3
Gene Summary	Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

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Amount: 100 ug

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Delivery expected until 9/6/2024