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HSPC111 Antibody (monoclonal) (M01)

HSPC111 Antibody (monoclonal) (M01)

Item no.	ABC-AT2451a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB, IF, IHC, ELISA
Clone	1G4
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NOP16, Nucleolar protein 16, HBV pre-S2 trans-regulated protein 3
Available
Primary Accession	Q9Y3C1
Antigen Type	Recombinant Protein
Application	WB, IHC, IF, E
Bio Background	NOP16 is transcriptionally regulated by c-Myc (MYC; MIM 190080), upregulated in breast cancer, and overexpression is associated with poor patient survival (Butt et al., 2008).
Bio References	The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome. Butt AJ, et al. Breast Cancer Res, 2008. PMID 18373870.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Generation and initial analysis of more than 15, 000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.Functional proteomic analysis of human nucleolus. Scherl A, et al. Mol Biol Cell, 2002 Nov. PMID 12429849.Directed proteomic analysis of the human nucleolus. Andersen JS, et al. Curr Biol, 2002 Jan 8. PMID 11790298.
Clonality	Monoclonal
Gene ID	51491
Gene Name	NOP16
Subtitle	Mouse monoclonal antibody raised against a full length recombinant HSPC111.
Reactivity	H
Legend image 1	Immunofluorescence of monoclonal antibody to HSPC111 on HeLa cell. [antibody concentration 10 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (45.32 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	HSPC111 monoclonal antibody (M01), clone 1G4 Western Blot analysis of HSPC111 expression in K-562 ( (Cat # AT2451a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	Immunoperoxidase of monoclonal antibody to HSPC111 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]
Type image 4	IHC
Legend image 5	Detection limit for recombinant GST tagged HSPC111 is approximately 1ng/ml as a capture antibody.
Type image 5	E
Other Accession	BC040106
Isotype	IgG1 Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	HSPC111 (AAH40106, 1 a.a. ~ 178 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_001243468.1; NP_001243469.1; NP_057475.2
	Clone: 1G4
Org Accession	AAH40106
Gene Description	NOP16 nucleolar protein homolog (yeast)
Gene Summary	NOP16 is transcriptionally regulated by c-Myc (MYC; MIM 190080), upregulated in breast cancer, and overexpression is associated with poor patient survival (Butt et al., 2008).[supplied by OMIM

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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