Item no. |
ABC-AT2132a |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Format |
Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Applications |
WB, IHC, ELISA |
Clone |
4C4 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CDH1, FZR1, FYR, FZR, KIAA1242, Fizzy-related protein homolog, CDC20-like protein 1, Cdh1/Hct1 homolog, Fzr, hCDH1 |
Available |
|
Primary Accession |
Q9UM11 |
Antigen Type |
Recombinant Protein |
Application |
WB, IHC, E |
Bio References |
The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation. Naoe H, et al. Mol Cell Biol, 2010 Aug. PMID 20530197.Centrosome-related genes, genetic variation, and risk of breast cancer. Olson JE, et al. Breast Cancer Res Treat, 2010 May 28. PMID 20508983.Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis. Sigl R, et al. J Cell Sci, 2009 Nov 15. PMID 19861496.The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Bassermann F, et al. Cell, 2008 Jul 25. PMID 18662541.Dissection of the APCCdh1-Skp2 cascade in breast cancer. Fujita T, et al. Clin Cancer Res, 2008 Apr 1. PMID 18381934. |
Clonality |
Monoclonal |
Gene ID |
51343 |
Gene Name |
|
Subtitle |
Mouse monoclonal antibody raised against a full-length recombinant FZR1. |
Reactivity |
H |
Legend image 1 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (80.08 KDa) . |
Type image 1 |
WB |
Dilution image 1 |
1:500~1000 |
Legend image 2 |
FZR1 monoclonal antibody (M02), clone 4C4. Western Blot analysis of FZR1 expression in Hela S3 NE. |
Type image 2 |
WB |
Dilution image 2 |
1:500~1000 |
Legend image 3 |
Immunoperoxidase of monoclonal antibody to FZR1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] |
Type image 3 |
IHC |
Legend image 4 |
Detection limit for recombinant GST tagged FZR1 is 1 ng/ml as a capture antibody. |
Type image 4 |
E |
Legend image 5 |
Proximity Ligation Analysis of protein-protein interactions between CCNB1 and FZR1. HeLa cells were stained with anti-CCNB1 rabbit purified polyclonal 1:1200 and anti-FZR1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue). |
Other Accession |
BC013413 |
Isotype |
IgG2a Kappa |
Antigen Source |
Human: ~~ Positive |
Target/Specificity |
FZR1 (AAH13413.1, 1 a.a. ~ 493 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
NCBI Accession |
NP_001129669.1; NP_001129670.1; NP_057347.2 |
|
Clone: 4C4 |
Org Accession |
AAH13413.1 |
Gene Description |
fizzy/cell division cycle 20 related 1 (Drosophila) |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.