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EXO1 Antibody (monoclonal) (M01)

EXO1 Antibody (monoclonal) (M01)

Item no.	ABC-AT1962a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB
Clone	1G12
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	EXO1, Exonuclease 1, HEX1, hExoI, Exonuclease I, hExo1, 31--, EXOI
Available
Primary Accession	Q9UQ84
Antigen Type	Recombinant Protein
Application	WB
Bio Background	This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
Bio References	A Large-scale genetic association study of esophageal adenocarcinoma risk. Liu CY, et al. Carcinogenesis, 2010 Jul. PMID 20453000.Delineation of WRN helicase function with EXO1 in the replicational stress response. Aggarwal M, et al. DNA Repair (Amst), 2010 Jul 1. PMID 20447876.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Single-nucleotide polymorphism of the Exo1 gene: association with gastric cancer susceptibility and interaction with smoking in Taiwan. Bau DT, et al. Chin J Physiol, 2009 Dec 31. PMID 20337148.Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA. Vallur AC, et al. PLoS One, 2010 Jan 26. PMID 20126648.
Clonality	Monoclonal
Gene ID	9156
Gene Name	EXO1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant EXO1.
Reactivity	H
Legend image 1	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
Type image 1	WB
Dilution image 1	1:500~1000
Legend image 2	EXO1 monoclonal antibody (M01), clone 1G12 Western Blot analysis of EXO1 expression in A-431 ( (Cat # AT1962a )
Type image 2	WB
Dilution image 2	1:500~1000
Other Accession	BC007491
Isotype	IgG1 Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	EXO1 (AAH07491, 747 a.a. ~ 846 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_003677.4; NP_006018.4; NP_569082.2
	Clone: 1G12
Org Accession	AAH07491
Gene Description	exonuclease 1
Gene Summary	This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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