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CDC42EP2 Antibody (monoclonal) (M01)

CDC42EP2 Antibody (monoclonal) (M01)

Item no.	ABC-AT1466a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB
Clone	2H7
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CDC42EP2, BORG1, CEP2, Cdc42 effector protein 2, Binder of Rho GTPases 1
Available
Primary Accession	O14613
Antigen Type	Recombinant Protein
Application	WB
Bio Background	CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.
Bio References	1.Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with CDC42 effector proteins.Schnack C, Danzer KM, Hengerer B, Gillardon F.Neuroscience. 2008 Jul 17; 154(4):1450-7. Epub 2008 Feb 29.
Clonality	Monoclonal
Gene ID	10435
Gene Name	CDC42EP2
Subtitle	Mouse monoclonal antibody raised against a partial recombinant CDC42EP2.
Reactivity	H
Legend image 1	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .
Type image 1	WB
Dilution image 1	1:500~1000
Legend image 2	Western Blot analysis of CDC42EP2 expression in transfected 293T cell line by CDC42EP2 monoclonal antibody (M01), clone 2H7. Lane 1: CDC42EP2 transfected lysate(22.5 KDa). Lane 2: Non-transfected lysate.
Type image 2	WB
Dilution image 2	1:500~1000
Other Accession	NM_006779
Isotype	IgG1 Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	CDC42EP2 (NP_006770, 102 a.a. ~ 210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_006770.1
	Clone: 2H7
Org Accession	NP_006770
Gene Description	CDC42 effector protein (Rho GTPase binding) 2
Gene Summary	CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq

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