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CCNG1 Antibody (monoclonal) (M01)

CCNG1 Antibody (monoclonal) (M01)

Item no.	ABC-AT1420a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	ELISA
Clone	1000
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis. Cunningham JM, et al. Br J Cancer, 2009 Oct 20. PMID 19738611.MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells. Fornari F, et al. Cancer Res, 2009 Jul 15. PMID 19584283.Lysine-independent turnover of cyclin G1 can be stabilized by B'alpha subunits of protein phosphatase 2A. Li H, et al. Mol Cell Biol, 2009 Feb. PMID 18981217.A role for the cyclin box in the ubiquitin-mediated degradation of cyclin G1. Piscopo DM, et al. Cancer Res, 2008 Jul 15. PMID 18632610.Cdk5-mediated phosphorylation of c-Myc on Ser-62 is essential in transcriptional activation of cyclin B1 by cyclin G1. Seo HR, et al. J Biol Chem, 2008 Jun 6. PMID 18408012.
NCBI	NP_004051.1,NP_954854.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cyclin-G1,Cyclin-G,CCNG1,CCNG,CYCG1
Similar products	CCNG1, CCNG, CYCG1, Cyclin-G1, Cyclin-G
Available
Manufacturer - Targets	CCNG1 (AAH00196, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
Clonality	Monoclonal
Gene Name	CCNG1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant CCNG1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Org Accession	AAH00196
Gene Description	cyclin G1
Gene Summary	The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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