Item no. |
ABC-ASC11963 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Applications |
WB, IHC, ELISA |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Available |
|
Primary Accession |
Q6NUI6 |
Application |
WB, IHC, E |
Bio Background |
The Chondroadherin-like (CHADL) protein, also known as SLRR4B, is homologous to the Chondroadherin protein and is expressed cartillaginous tissues (1). Like Chondroadherin, CHADL belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1, 2). CHADL is thought to play a negative regualtory role in collagen fibrillogenesis and chondrocyte differentiation (1). |
Bio References |
Tillgren V, Ho JC, Onnerfjord P, et al. The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentitation. J. Biol. Chem. 2015; 290:918-25.Neame PJ, Sommarin Y, Boynton RE, et al. The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage. J. Biol. Chem. 1994; 269:21547-54. |
Clonality |
Polyclonal |
Gene ID |
150356 |
Gene Name |
CHADL |
Reactivity |
H, M, Rat |
Legend image 1 |
Immunofluorescence of SOX2 in mouse brain tissue with SOX2 Antibodyat 20 µg/mL. |
Type image 1 |
IF |
Other Accession |
NP_612490; 150356 |
Isotype |
IgG |
Calculated MW |
82388 |
Antigen Source |
homo sapiens |
Target/Specificity |
CHADL antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CHADL.
The immunogen is located within the last 50 amino acids of CHADL. |
Purification |
CHADL Antibody is affinity chromatography purified via peptide column. |
Reconstitution & Storage |
CHADL antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
Antibody Form |
Liquid |
Application Notes |
CHADL antibody can be used for the detection of CHADL by Western blot at 1 - 2 μ g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ g/mL. |
Positive Control |
Rat Skeletal Muscle Tissue Lysate; |
Buffer |
CHADL Antibody is supplied in PBS containing 0.02% sodium azide. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.