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EPM2A Antibody

EPM2A Antibody

Item no.	ABC-ASC11542
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IF, ICC, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Primary Accession	O95278
Application	WB, IF, ICC, E
Bio Background	EPM2A Antibody: The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
Bio References	Minassian BA, Lee JR, Herbrick JA, et al. Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy. Nat. Genet. 1998; 20:171-4. Worby CA, Gentry MS, and Dixon JE. Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates. J. Biol. Chem. 2006; 281:30412-8.
Clonality	Polyclonal
Gene ID	7957
Gene Name	EPM2A
Reactivity	H, M, Rat
Legend image 1	Western blot analysis of SW480 in SW480 cell lysate with EPM2A antibody at (A) 1 and (B) 2 µg/mL.
Type image 1	WB
Legend image 2	Immunocytochemistry of EPM2A in SW480 cells with EPM2A antibody at 2.5 µg/ml.
Type image 2	ICC
Legend image 3	Immunofluorescence of EPM2A in SW480 cells with EPM2A antibody at 5 µg/ml.
Type image 3	IF
Other Accession	NP_005661; 11321613
Isotype	IgG
Calculated MW	37158
Antigen Source	homo sapiens
Target/Specificity	EPM2A; At least four isoforms of EPM2A are known to exist; this antibody will detect all but the shortest isoform.
Purification	EPM2A Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage	EPM2A antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody Form	Liquid
Application Notes	EPM2A antibody can be used for detection of EPM2A by Western blot at 1 - 2 µg/mL.
Positive Control	SW480 Cell Lysate;
Buffer	EPM2A Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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