Item no. |
ABC-ASC11437 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Applications |
WB, ICC, ELISA |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Available |
|
Primary Accession |
Q9NU39 |
Application |
WB, ICC, E |
Bio Background |
FOXD4L1 Antibody: FOXD4L1, also known as FOXD5, is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains. Members of the FOX family of transcription factors are regulators of embryogenesis and is thought to play a role in human cancer. FOXD4L1 is a forkhead transcription factor that functions as both a transcriptional activator and repressor and acts upstream of several other neural transcription factors to maintain neural fate, regulate neural plate patterning, and delay the expression of neural differentiation factors. |
Bio References |
Jackson BC, Carpenter C, Nebert DW, et al. Update of human and mouse forkhead box (FOX) gene families. Hum. Genomics 2010; 4:345-52.Yan B, Neilson KM, and Moody SA. Microarray identification of novel downstream targets of FoxD4L1/D5, a critical component of the neural ectodermal transcriptional network. Dev. Dyn. 2010; 239:3467-80. |
Clonality |
Polyclonal |
Gene ID |
200350 |
Gene Name |
FOXD4L1 |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of FOXD4L1 in A-20 cell lysate with FOXD4L1 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide. |
Type image 1 |
WB |
Legend image 2 |
Immunocytochemistry of FOXD4L1 in MCF7 cells with FOXD4L1 antibody at 10 µg/ml. |
Type image 2 |
ICC |
Other Accession |
NP_036316; 18959276 |
Isotype |
IgG |
Calculated MW |
43610 |
Antigen Source |
Homo sapiens |
Target/Specificity |
FOXD4L1; This antibody is predicted to not cross-react with any FOXD4 protein family members |
Purification |
FOXD4L1 Antibody is affinity chromatography purified via peptide column. |
Reconstitution & Storage |
FOXD4L1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Antibody Form |
Liquid |
Application Notes |
FOXD4L1 antibody can be used for detection of FOXD4L1 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry at 10 µg/ml. |
Positive Control |
A-20 Cell Lysate; |
Buffer |
FOXD4L1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.