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DBX1 Antibody

DBX1 Antibody

Item no.	ABC-ASC11366
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IF, ELISA, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Primary Accession	A6NMT0
Application	WB, IHC-P, IF, E
Bio Background	DBX1 Antibody: DBX1 is implicated in patterning the central nervous system during embryogenesis. DBX1 homeodomain transcription factor is expressed in progenitors which are critical in establishing cell fate allocation and cell diversity. DBX1 has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. DBX1-derived neurons are essential for the transgenic expression and generation of respiratory behavior both in vitro and in vivo.
Bio References	Griveau A, Borello U, Causeret F, et al. A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepithelium. PLoS Biol. 2010; 8(7):e1000440 Causeret F, Ensini M, Teissier A, et al. Dbx1-expressing cells are necessary for the survival of the Mammalian anterior neural and craniofacial structures. PLoS One 2011; 6:e19367. Pierani A, Moran-Rivard L, Sunshine MJ, et al. Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. Neuron 2001; 29:367-84 Gray PA, Hayes JA, Ling GY, et al. Developmental origin of preBotzinger complex respiratory neurons. J. Neurosci. 2010; 30:14883-95.
Clonality	Polyclonal
Gene ID	120237
Gene Name	DBX1
Reactivity	H, M, Rat
Legend image 1	Western blot analysis of DBX1 in mouse kidney tissue lysate with DBX1 antibody at (A) 1 and (B) 2 µg/mL.
Type image 1	WB
Legend image 2	Immunohistochemistry of DBX1 in human kidney tissue with DBX1 antibody at 2.5 µg/mL.
Type image 2	IHC
Legend image 3	Immunofluorescence of DBX1 in human kidney tissue with DBX1 antibody at 20 µg/mL.
Type image 3	IF
Other Accession	NP_001025036; 304434796
Isotype	IgG
Calculated MW	37283
Antigen Source	Homo sapiens
Target/Specificity	DBX1; BX1 antibody is predicted to not cross-react with other DBX protein family members
Purification	DBX1 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage	DBX1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody Form	Liquid
Application Notes	DBX1 antibody can be used for detection of DBX1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Positive Control	Mouse Kidney Tissue Lysate;
Buffer	DBX1 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/8/2024

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