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ApoA1 Antibody

ApoA1 Antibody

Item no.	ABC-ASC11311
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Primary Accession	P02647
Application	WB, E
Bio Background	ApoA1 Antibody: Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma, which is correlated with cardiovascular disease. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.
Bio References	Zhu X, Wu G, Zeng W, et al. Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties. J. Lipid Res. 2005; 46:1303-11 Sorci-Thomas MG, Prack MM, Dashti N, et al. Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins. J. Lipid Res. 1989; 30:1397-403 Lai C-Q, Parnell LD, and Ordovas JM. The APOA1 /C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk. Curr. Opin. Lipid. 2005; 16:153-66
Clonality	Polyclonal
Gene ID	335
Gene Name	APOA1 (HGNC:600)
Reactivity	H, C
Legend image 1	Western blot analysis of ApoA1 in chicken liver tissue lysate with ApoA1 antibody at 1 µg/mL .
Type image 1	WB
Other Accession	P02647; 113992
Isotype	IgG
Calculated MW	30778
Antigen Source	Homo sapiens
Target/Specificity	APOA1;
Purification	ApoA1 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage	ApoA1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody Form	Liquid
Application Notes	ApoA1 antibody can be used for detection of ApoA1 by Western blot at 1 µg/mL.
Positive Control	;
Buffer	ApoA1 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-ASC11311-datasheet.pdf

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Amount: 100 ug

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Delivery expected until 10/4/2024

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