ZIP6 Antibody

Q13433

ZIP6 Antibody: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

Polyclonal

SLC39A6

Western blot analysis of ZIP6 in mouse lung tissue lysate with ZIP6 antibody at 1 µg/mL.

Immunohistochemistry of ZIP6 in mouse lung tissue with ZIP6 antibody at 5 µg/mL.

Immunofluorescence of ZIP6 in mouse lung tissue with ZIP6 antibody at 20 µg/mL.

NP_001092876; 153252214

85047

SLC39A6;

ZIP6 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ZIP6 antibody can be used for detection of ZIP6 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.

ZIP6 Antibody is supplied in PBS containing 0.02% sodium azide.