Item no. |
ABC-ASC11007 |
Manufacturer |
Abcepta
|
Amount |
100 ug |
Category |
|
Type |
Antibody Primary |
Applications |
WB, IF, ELISA |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Available |
|
Primary Accession |
Q56VL3 |
Application |
WB, IF, E |
Bio Background |
OCIAD2 Antibody: OCIAD2 was identified by its sequence similarity with OCIAD1, and together OCIAD1 and OCIAD2 form the OCIA domain family. OCIAD2 mRNA was found to be expressed at higher levels in invasive adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component (BAC) of the lung. Loss of OCIAD2 expression was significantly correlated with lymphatic invasion, blood vessel invasion, and lymph node metastasis, indicating that OCIAD2 may play a role in cell adhesion and prevention of cell migration. While the function of OCIAD2 is still unknown, its expression in adenocarcinoma with BAC component is significantly associated with a favorable prognosis and may serve as a marker for selecting tumors that are treatable by limited surgery. |
Bio References |
Strausberg RL, Feingold EA, Grouse LH, et al. Mammalian gene collection program team. Generation and initial analysis of more than 15, 000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA2002; 99:16899-903.Ishiyama T, Kano J, Anami Y, et al. OCIA domain containing 2 is highly expressed in adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component and is associated with better prognosis. Cancer Sci.2006; 98:50-7. |
Clonality |
Polyclonal |
Gene ID |
132299 |
Gene Name |
OCIAD2 |
Reactivity |
H |
Legend image 1 |
Western blot analysis of OCIAD2 in A549 cell lysate with OCIAD2 antibody at (A) 0.5 and (B) 1 µg/mL. |
Type image 1 |
WB |
Legend image 2 |
Immunofluorescence of OCIAD2 in A549 cells with OCIAD2 antibody at 5 µg/mL. |
Type image 2 |
IF |
Other Accession |
NP_001014446; 62244044 |
Isotype |
IgG |
Calculated MW |
16954 |
Antigen Source |
Homo sapiens |
Target/Specificity |
OCIAD2; |
Purification |
OCIAD2 Antibody is affinity chromatography purified via peptide column. |
Reconstitution & Storage |
OCIAD2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Antibody Form |
Liquid |
Application Notes |
OCIAD2 antibody can be used for detection of OCIAD2 by Western blot at 0.5 - 1 µg/mL. Antibody can also be used for immunoflourescence starting at 5 µg/mL. For immunofluorescence start at 5 µg/mL. |
Positive Control |
A549 Cell Lysate ; |
Buffer |
OCIAD2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.