ELOVL6 Antibody

Q9H5J4

ELOVL6 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Polyclonal

ELOVL6 {ECO:0000255|HAMAP-Rule:MF_03206}

Western blot analysis of ELOVL6 in Human brain tissue lysate with ELOVL6 antibody at (A) 1 and (B) 2 µg/mL.

Immunohistochemistry of ELOVL6 in human brain tissue with ELOVL6 antibody at 5 µg/mL.

Immunofluorescence of ELOVL6 in Human Brain tissue with ELOVL6 antibody at 20 µg/mL.

NP_076995; 13129088

31376

ELOVL6;

ELOVL6 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELOVL6 antibody can be used for detection of ELOVL6 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.

ELOVL6 Antibody is supplied in PBS containing 0.02% sodium azide.