CARD9 Antibody

Q9H257

CARD9 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-κB. CARD9 is an upstream activator of BCL-10 and NF-κB signaling.

Polyclonal

CARD9 {ECO:0000303|PubMed:11053425, ECO:0000312|HGNC:HGNC:16391}

Western blot analysis of CARD9 expression in human MDA-MB-361 (A) and PC-3 (B) cell lysate with CARD9 antibody at 2.5 µg /ml.

Immunocytochemistry of CARD9 in K562 cells with CARD9 antibody at 10 µg/mL.

AF311287; 11066983

62241

CARD9;

CARD9 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

CARD9 antibody can be used for detection of CARD9 by Western blot at 2.5 µg/mL. A band at approximately 59 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 µg/mL.

CARD9 Antibody is supplied in PBS containing 0.02% sodium azide.