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RNF8 Antibody

RNF8 Antibody

Item no.	ABC-AP9820a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	RNF8, KIAA0646, E3 ubiquitin-protein ligase RNF8, RING finger protein 8, hRNF8, 632-
Available
Primary Accession	O76064
Antigen Type	Recombinant Protein
Application	FC, WB
Bio Background	RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.
Bio References	Noon, A.T., et al. Nat. Cell Biol. 12(2):177-184(2010) Ramachandran, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(2):809-814(2010) Marteijn, J.A., et al. J. Cell Biol. 186(6):835-847(2009) Gong, Z., et al. J. Biol. Chem. 284(11):7284-7293(2009) Zhang, S., et al. Cell Cycle 7(21):3399-3404(2008)
Clonality	Polyclonal
Clone/Animal Names	RB22159
Gene ID	9025
Gene Name	RNF8 {ECO:0000255\|HAMAP-Rule:MF_03067}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of RNF8 Antibody (Cat. #AP9820a) in Jurkat cell line lysates (35ug/lane). RNF8 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	RNF8 Antibody (Cat. #AP9820a) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2	FC
Dilution image 2	1:10~50
Isotype	Rabbit Ig
Calculated MW	55518
Antigen Source	HUMAN
Target/Specificity	This RNF8 antibody is generated from rabbits immunized with recombinant protein of human RNF8.
NCBI Accession	NP_003949.1; NP_898901.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 10/4/2024

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