Comparison

CYTH3 Antibody (C-term)

Item no. ABC-AP9673B-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cytohesin-3, ARF nucleotide-binding site opener 3, Protein ARNO3, General receptor of phosphoinositides 1, Grp1, PH, SEC7 and coiled-coil domain-containing protein 3, CYTH3, ARNO3, GRP1, PSCD3
Available
Primary Accession
O43739
Other Accession
P97696; O08967
Antigen Type
Synthetic Peptide
Bio Background
This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1.
Bio References
Morishige, M., et al. Nat. Cell Biol. 10(1):85-92(2008)
Poirier, M.B., et al. Mol. Endocrinol. 19(8):1991-2005(2005)
Nevrivy, D.J., et al. J. Biol. Chem. 275(22):16827-16836(2000)
Ogasawara, M., et al. J. Biol. Chem. 275(5):3221-3230(2000)
Gene ID
9265
Gene Name
CYTH3 (HGNC:9504)
Reactivity
H, M
Predicted
Rat
Calculated MW
46349
Antigen Region
371-400
Antigen Source
HUMAN
Target/Specificity
This CYTH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-400 amino acids from the C-terminal region of human CYTH3.
NCBI Accession
NP_004218.1

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Amount: 80 ul
Available: Out of stock
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