Item no. |
ABC-AP8906B-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
A disintegrin and metalloproteinase with thrombospondin motifs 18, 3424-, ADAMTS18, ADAMTS21, ADAM-TS 18, ADAM-TS18, ADAMTS-18 |
Available |
|
Primary Accession |
Q8TE60 |
Antigen Type |
Synthetic Peptide |
Application |
FC, WB, IHC-P |
Bio Background |
ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. |
Bio References |
Zeng, W., et.al., Biochim. Biophys. Acta 1760 (3), 517-524 (2006)Jin, H., et.al., Oncogene 26 (53), 7490-7498 (2007) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB22477 |
Gene ID |
170692 |
Gene Name |
ADAMTS18 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of ADAMTS18 Antibody (C-term) (Cat. #AP8906b) in mouse liver tissue lysates (35ug/lane). ADAMTS18 (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
ADAMTS18 Antibody (C-term) (Cat. #AP8906b) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ADAMTS18 antibody detected the ADAMTS18 protein (arrow). |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
Formalin-fixed and paraffin-embedded human brain tissue reacted with ADAMTS18 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 3 |
IHC-P |
Dilution image 3 |
1:50~100 |
Legend image 4 |
ADAMTS18 Antibody (C-term) (Cat. #AP8906b) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 4 |
FC |
Dilution image 4 |
1:10~50 |
Isotype |
Rabbit Ig |
Calculated MW |
135167 |
Antigen Region |
1066-1095 |
Antigen Source |
HUMAN |
Target/Specificity |
This ADAMTS18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1066-1095 amino acids from the C-terminal region of human ADAMTS18. |
NCBI Accession |
NP_955387.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.