Item no. |
ABC-AP8416a-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
PTPRE, Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon |
Available |
|
Primary Accession |
P23469 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
PTPepsilon is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of the gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. |
Bio References |
Toledano-Katchalski, H., et al., Mol. Cell. Biol. 23(15):5460-5471 (2003).Blanchetot, C., et al., J. Biol. Chem. 277(49):47263-47269 (2002).Wabakken, T., et al., Scand. J. Immunol. 56(3):276-285 (2002).Wabakken, T., et al., Scand. J. Immunol. 56(2):195-203 (2002).Tanuma, N., et al., J. Biol. Chem. 275(36):28216-28221 (2000). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB0551 |
Gene ID |
5791 |
Gene Name |
PTPRE |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Abgent invites you to submit your data (IHC, IF, IP, WB, FC) using this product. We will award you credits, 50% of the cost you paid, for future purchases. For availability of this promotion please contact us at tech@abgent.com. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Isotype |
Rabbit Ig |
Calculated MW |
80642 |
Antigen Region |
558-589 |
Antigen Source |
HUMAN |
Target/Specificity |
This PTP epsilon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-589 amino acids from the C-terminal region of human PTP epsilon. |
NCBI Accession |
NP_006495.1; NP_569119.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.