Comparison

ITPKA Antibody (N-term)

Item no. ABC-AP8166a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Inositol-trisphosphate 3-kinase A, Inositol 1,5-trisphosphate 3-kinase A, IP3 3-kinase A, IP3K A, InsP 3-kinase A, ITPKA
Available
Primary Accession
P23677
Other Accession
NP_002211
Antigen Type
Synthetic Peptide
Bio Background
ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of the inositol 1, 4, 5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.
Bio References
Gonzalez, B., et al., Mol. Cell 15(5):689-701 (2004).
Mishra, J., et al., Biophys. J. 83(3):1298-1316 (2002).
Schell, M.J., et al., J. Biol. Chem. 276(40):37537-37546 (2001).
Communi, D., et al., EMBO J. 16(8):1943-1952 (1997).
Woodring, P.J., et al., J. Biol. Chem. 272(48):30447-30454 (1997).
Gene ID
3706
Gene Name
ITPKA
Reactivity
H
Calculated MW
51009
Antigen Region
1-30
Antigen Source
HUMAN
Target/Specificity
This ITPKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ITPKA.
NCBI Accession
NP_002211.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 80 ul
Available: Out of stock
Questions about this Product?
 
Close