Item no. |
ABC-AP8152d-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
YWHAZ, 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1 |
Available |
|
Primary Accession |
P63104 |
Antigen Type |
Synthetic Peptide |
Application |
WB, IHC-P |
Bio Background |
14-3-3 protein zeta/delta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. |
Bio References |
Li, F.Q., J. Cell Biol. 181 (7), 1141-1154 (2008)Mateo, I., Eur. J. Neurol. 15 (3), 219-222 (2008)Li, Z., Proc. Natl. Acad. Sci. U.S.A. 105 (1), 162-167 (2008)Powell, D.W., Mol. Cell. Biol. 23 (15), 5376-5387 (2003)Powell, D.W., J. Biol. Chem. 277 (24), 21639-21642 (2002) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB7161 |
Gene ID |
7534 |
Gene Name |
YWHAZ |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of anti-14-3-3 protein zeta/delta Anbtibody (T232)(Cat.#AP8152d) in A375 cell line lysates (35ug/lane). 14-3-3 (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Formalin-fixed and paraffin-embedded human testis tissue reacted with YWHAZ Antibody (Cat.#AP8152d), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
P63102; P63101; Q5ZKC9; P63103; P29361 |
Predicted |
B, C, M, Rat, Sh |
Isotype |
Rabbit Ig |
Calculated MW |
27745 |
Antigen Region |
211-239 |
Antigen Source |
HUMAN |
Target/Specificity |
This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from human YWHAZ. |
NCBI Accession |
NP_001129171.1; NP_001129172.1; NP_001129173.1; NP_001129174.1; NP_003397.1; NP_663723.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.