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BUB1 (BUB1a) Antibody (C-term)

BUB1 (BUB1a) Antibody (C-term)

Item no.	ABC-AP8058b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BUB1, BUB1L, Mitotic checkpoint serine/threonine-protein kinase BUB1, BUB1A, hBUB1
Available
Primary Accession	O43683
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.
Bio References	Shichiri, M., et al., Cancer Res. 62(1):13-17 (2002). Cayrol, C., et al., Biochem. Biophys. Res. Commun. 298(5):720-730 (2002). Nakagawa, H., et al., Oncol. Rep. 9(6):1229-1232 (2002). Ru, H.Y., et al., Oncogene 21(30):4673-4679 (2002). Lin, S.F., et al., Leuk. Lymphoma 43(2):385-391 (2002).
Clonality	Polyclonal
Clone/Animal Names	RB03123-03124
Gene ID	699
Gene Name	BUB1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	BUB1A Antibody (F1058) (Cat.#AP8058b) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the BUB1A antibody detected the BUB1A protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	122375
Antigen Region	1043-1073
Antigen Source	HUMAN
Target/Specificity	This BUB1 (BUB1a) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1043-1073 amino acids from the C-terminal region of human BUB1 (BUB1a).
NCBI Accession	NP_004327.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 11/8/2024

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