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PIP4K2 Alpha (PIP4K2A) Antibody (C-term)

PIP4K2 Alpha (PIP4K2A) Antibody (C-term)

Item no.	ABC-AP8041b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PIP4K2A, PIP5K2, PIP5K2A, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha, Diphosphoinositide kinase 2-alpha, PIP5KIII, Phosphatidylinositol 5-phosphate 4-kinase type II alpha, PI(5)P 4-kinase type II alpha, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PIP4KII-alpha, PtdIns(5)P-4-kinase isoform 2-alpha
Available
Primary Accession	P48426
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Phosphatidylinositol-4, 5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. TPIP5K2A is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4, 5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. The protein is a member of the phosphatidylinositol-4-phosphate 5-kinase family.
Bio References	Rozenvayn, N., et al., J. Biol. Chem. 278(10):8126-8134 (2003). Boronenkov, I.V., et al., J. Biol. Chem. 270(7):2881-2884 (1995). Loijens, J.C., et al., Adv. Enzyme Regul. 36, 115-140 (1996). Divecha, N., et al., Biochem. J. 309 (Pt 3), 715-719 (1995).
Clonality	Polyclonal
Clone/Animal Names	RB1741
Gene ID	5305
Gene Name	PIP4K2A (HGNC:8997)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-PIP4K2A Pab (Cat. #AP8041b) in HL60 cell lysate. PIP5K2A (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	Q9R0I8; O13010; O70172; NP_005019
Predicted	M, Pig, Rat
Isotype	Rabbit Ig
Calculated MW	46225
Antigen Region	303-335
Antigen Source	HUMAN
Target/Specificity	This PIP4K2 Alpha (PIP4K2A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-335 amino acids from the C-terminal region of human PIP4K2 Alpha (PIP4K2A).
NCBI Accession	NP_005019.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 10/4/2024