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NIK Antibody (Center)

NIK Antibody (Center)

Item no.	ABC-AP7967c-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Hematology Myeloma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, HsNIK, Serine/threonine-protein kinase NIK, MAP3K14, NIK
Available
Primary Accession	Q99558
Antigen Type	Synthetic Peptide
Bio Background	NIK (mitogen-activated protein kinase kinase kinase 14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Bio References	Andreakos, E., et al., Blood 101(3):983-991 (2003). Ninomiya-Tsuji, J., et al., Nature 398(6724):252-256 (1999). Aronsson, F.C., et al., Hum. Genet. 103(3):340-345 (1998). Lin, X., et al., Mol. Cell. Biol. 18(10):5899-5907 (1998). Malinin, N.L., et al., Nature 385(6616):540-544 (1997).
Gene ID	9020
Gene Name	MAP3K14
Reactivity	H
Calculated MW	104042
Antigen Region	119-148
Antigen Source	HUMAN
Target/Specificity	This NIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human NIK.
NCBI Accession	NP_003945.2

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Amount: 80 ul

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