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AAK1 Antibody (C-term)

AAK1 Antibody (C-term)

Item no.	ABC-AP7861B-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AP2-associated protein kinase 1, Adaptor-associated kinase 1, AAK1, KIAA1048
Available
Primary Accession	Q2M2I8
Other Accession	P0C1X8; F1SPM8; Q3UHJ0; F1MH24
Antigen Type	Synthetic Peptide
Bio Background	Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
Bio References	Henderson, D.M., Mol. Biol. Cell 18 (7), 2698-2706 (2007) Takahashi, T., Cancer Res. 66 (24), 11932-11937 (2006) Schmid, E.M., PLoS Biol. 4 (9), E262 (2006)
Gene ID	22848
Gene Name	AAK1
Reactivity	H
Predicted	B, M, Pig, Rat
Calculated MW	103885
Antigen Region	790-819
Antigen Source	HUMAN
Target/Specificity	This AAK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 790-819 amino acids from the C-terminal region of human AAK1.
NCBI Accession	NP_055726.3

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Amount: 80 ul

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