« Back
Home /
TGF Beta Receptor I Antibody (Center)

TGF Beta Receptor I Antibody (Center)

Item no.	ABC-AP7822c-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Neuroinflammation Neural Signaling Antibodies Carcinoma Glioma Cell Biology Cell Culture Cytokines Mesothelioma Immunohistochemistry Western Blot Primary Antibodies Colorectal Cancer
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TGF-beta receptor type-1, TGFR-1, Activin A receptor type II-like protein kinase of 53kD, Activin receptor-like kinase 5, ALK-5, ALK5, Serine/threonine-protein kinase receptor R4, SKR4, TGF-beta type I receptor, Transforming growth factor-beta receptor ty
Available
Primary Accession	P36897
Other Accession	P80204; Q5CD18; Q64729; O46680
Antigen Type	Synthetic Peptide
Bio Background	The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
Bio References	Itoh, S., et al., J. Biol. Chem. 278(6):3751-3761 (2003). Valcourt, U., et al., J. Biol. Chem. 277(37):33545-33558 (2002). Bourguignon, L.Y., et al., J. Biol. Chem. 277(42):39703-39712 (2002). Jude, E.B., et al., Diabet. Med. 19(6):440-447 (2002). Nagel, D., et al., Biochem. Biophys. Res. Commun. 290(5):1558-1563 (2002).
Gene ID	7046
Gene Name	TGFBR1
Reactivity	H
Predicted	B, M, Pig, Rat
Calculated MW	55960
Antigen Region	134-163
Antigen Source	HUMAN
Target/Specificity	This TGF Beta Receptor I antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the Central region of human TGF Beta Receptor I.
NCBI Accession	NP_001124388.1; NP_004603.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 80 ul

not available